Waterloo, situated in the heart of the Finger Lakes area, is located between the northern-most tips of Seneca and Cayuga Lakes just five miles south of NYS Thruway exit #41. The downtown area is located at the intersection of Routes 5&20 and Route 96. Waterloo is centrally located between Rochester, Syracuse and Ithaca, NY… all three cities can be reached by car in less than one hour.